Animal Health Diagnostic Center

Cornell University

Improving the health of animals, animal populations and wildlife

Search Tests and Fees Shipping Instructions Sample Submission Guidance

Comparative Coagulation

Assay Reference Intervals

Tests APTT PT TCT Fibrinogen D dimer Antithrombin Protein C
Units (seconds) (seconds) (seconds) mg/dL ng/mL (%) (%)
Species
Canine 11.0 - 17.5 11.0 - 15.5 5.0 - 9.0 150 – 490 0 - 575 65 - 145 75 - 135
Feline 15.0 – 21.0 15.0 – 20.0 5.0 – 8.0 76 – 270 0 – 250 75 - 100 65 - 120
Equine 35.8 – 48.6 11.0 – 15.0 200 – 470 0 – 1000 85 - 130
Bovine 30.0 – 58.0 26.0 – 38.0 440 - 770
Alpaca 16.6 – 22.1 10.9 – 13.6 128 - 327
Rat (SD) 12.1 – 22.5 18.7 – 28.0 145 - 340
Dolphin 230 - 325

Assay Information

Test Assay
aPTT activated partial thromboplastin time; 3 minute activation time, ellagic acid reagent
PT prothrombin time; rabbit brain thromboplastin reagent
TCT thrombin clotting time; bovine thrombin reagent
Fibrinogen Clauss (clottable) fibrinogen; same species standard (canine, feline, equine) all others human standard
Antithrombin anti-IIa activity, chromogenic substrate; same species standard (canine, feline, equine) all others human standard
D dimer D dimer concentration, immunoturbidometric assay; human D dimer standard
Protein C snake venom activator, chromogenic substrate; same species standard (canine, feline) all others human standard

Contact us

240 Farrier Road
Ithaca, NY 14853

Business Hours
Monday-Friday:
8 a.m.-5 p.m.
Saturday (limited service):
9 a.m.-1 p.m.